bio-bgzf

https://github.com/csw/bioruby-bgzf

This library provides support for BGZF (Blocked GZip Format) in Ruby. BGZF, originally defined as part of the SAM/BAM specification, is used to compress record-oriented data in a way that facilitates random access, unlike plain gzip. BGZF is principally used for bioinformatics data but would be useful in other contexts as well.